The University of Notre Dame supports a number of core facilities and research resources that are available to on-campus researchers as well as external users. These research facilities support a vibrant research community and are fully staffed to provide expert guidance, support, and instrumentation for their users. 

Learn more about the core facilities located within McCourtney Hall below.

Chemical Synthesis and Drug Discovery

Chem Synth Tile

The Chemical Synthesis and Drug Discovery (CSDD) Facility supports translational biomedical research by providing expertise that enables the preparation of small molecules for use in hit verification, lead development, and midsize scale up. It supports the preparation of biological probes (affinity or fluorescently tagged), active pharmaceutical agents as experimental controls, and small chemical libraries for structure-activity relationships and the optimization of pharmacological properties.

In addition, the CSDD provides organizational oversight for the Notre Dame Chemical Compound Collection, which has more than 20,000 unique chemical entities. It is available to researchers from the Notre Dame research community, other academic institutions, and industry.

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Integrated Imaging Facility

Tile Facility Integrated Imaging

The Notre Dame Integrated Imaging Facility (NDIIF) integrates three areas of Notre Dame imaging expertise: electron microscopy, biological imaging (in vivo imaging and optical microscopy), and histology.

The NDIIF has an integrated suite of sophisticated microscopes and imaging stations that enable users to attack the most complex modern research problems. It is open to the Notre Dame research community, external academic institutions, and industry. Additionally, it is an approved Indiana Clinical and Translational Sciences Institute (CTSI) core facility, with services available to all CTSI partners.

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Magnetic Resonance Research Center

Tile Facility Magnetic Resonance

The Magnetic Resonance Research Center (MRRC) supports Notre Dame researchers in chemistry, biochemistry, molecular biology, chemical engineering, and related fields by providing nuclear magnetic resonance (NMR) analytical support. The MRRC has seven spectrometers available to Notre Dame researchers, other academic institutions, and off-campus corporations. All of the spectrometers are multinuclear and a large variety of probes are available. The spectrometers enable measurements of 1D and 2D homo- and heteronuclear spectra at various temperatures.

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Mass Spectometry and Proteomics

Tile Facility Spectrometry Proteomics

The Mass Spectrometry and Proteomics Facility (MSPF) provides modern instrumentation and expertise for the detection, identification, and quantification of compounds ranging from small organic molecules to large biomolecules with applications in areas including metabolomics, proteomics, and lipidomics.

With instrumentation in laboratory spaces in Stepan Chemistry Hall, the MSPF is available to both internal and external customers, including other academic institutions and industry. The MSPF is an approved Indiana CTSI core facility.

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